GEN Magazine

Volume 42, Issue No. 06, June 2022

Crops failing due to adverse weather conditions. Data infrastructure struggling to cope with burgeoning data loads. Patients being denied stem cell therapies because of immune rejection risks, or because manufacturing bottlenecks have yet to be resolved. These problems, and others, are discussed in the June issue of GEN. Our takes are decidedly optimistic. More resilient (and more nutritious) crops are being developed with CRISPR technology. Data infrastructure is beginning to comply with FAIR principles, which emphasize Findability, Accessibility, Interoperability, and Reusability. And stem cell therapies are overcoming immune resistance by deploying “medicinal signaling cells,” preserving the “stemness” of cord blood cells, and engineering T cells that can suppress immune responses in organ-specific ways. A less life-and-death (but still serious) stem cell application—overcoming hair loss—receives attention, too. Rounding out our June coverage, we present articles describing “digital twins,” increasingly quantitative mass spec platforms, and the economic challenges facing the nation’s top 10 biopharma clusters.

Browse the print magazine as a flipbook

Browse the print magazine supplement as a flipbook

Website Content from This Issue

From Pharma to Farm: Can CRISPR Feed the World?

vegetable crop

New Bead Technology Enables Commercial-Scale mRNA Purification

RNA, epigenetics concept

RNA Leaders Explore New Frontiers in mRNA-Based Medications

Ribonucleic acid strands consisting of nucleotides

With mRNA Technology, Vaccines and Therapeutics Stay on Message

photochemical internalization (PCI) technology

Developing Tomorrow’s mRNA-Based Therapies

Ribosome translating messenger RNA into a polypeptide chain

Stem Cell Companies Find Gratifying Niches

ViaCyte, viewing cells

Mass Spectrometry Resolves Nagging Ambiguities in Bioprocessing

proteins or enzymes

As Data Flows Surge, Data Infrastructure Groans

Hand Over DNA Sequence

Biopharma Is Going Digital … Bit by Bit

GSK Vaccines Wavre

Top 10 U.S. Biopharma Clusters

Bristol Myers Squibb building

Carbon Dots for Nanomedicine

DD Tutorial Figure 3

Hair Loss Treatment Uses Stem Cells to Generate Healthy New Follicles

Somatic cells

Overcoming the Challenges of Cell and Gene Therapy Facilities

Integrated Project Services biomanufacturing facility

Overcoming the DNA Bottleneck

DNA sequence, DNA code structure

Overcoming Challenges in Biological Data Management

AI pill robot

Serving Customers with Analytical Testing from Assay Design through Product Release

DNA helix 3D illustration

Orange Book Express



Smart Tasks

Smart tasks

Researcher: Discover & Discuss

Clinical-Grade Recombinant Proteins for Cell Therapy

Multi-Mode Microplate Reader

Molecular Devices

Improved Viral RNA Extraction from Nasal and Throat Swab samples

Porvair Sciences

NASH ‘In-A-Box’ Reagent Kit


Cell Types Resolved by scRNA-seq, Mapped across Human Tissues

Alzheimer’s Biomarker Researchers Suggest Caution with Dietary Supplement

alzhimer's disease

Sangamo Advances Kidney Transplant Cell Therapy into the Clinic