Streamlining Bioprocess Monitoring for Scale
The revelation last June that several sartans, a group of angiotensin II receptor blocker (ARB) high-blood pressure medications, were contained via their manufacturing process with potentially carcinogenic nitrosamines NDMA and NMEA highlights the need...
Antibody Characterization Keeps Pace with the Antibody Industry
Biologic monoclonal antibody (mAb) drugs are not just more targeted than small-molecule drugs, they are also larger, more complicated, and more variable. Consequently, biologic mAb drugs, which generate sizable revenues, may enjoy some degree...
Silencing Genes in Cellular Protein Factories Amplifies Production
The cellular factories that churn out recombinant proteins may adopt their own version of lean manufacturing: intensify everything that adds value and curtail everything else. To date, yeast and other tiny protein factories have...
Audentes Launches Internal cGMP Plasmid Manufacturing Facility
Audentes Therapeutics launched a new South San Francisco-based internal cGMP plasmid manufacturing facility which, the company says, is expected to significantly enhance a critical element of its supply chain, i.e., provide high-quality nonclinical and cGMP-grade...
Continual Improvements Advance Continuous Biomanufacturing
Continuous manufacturing is finally gaining traction in the pharmaceutical industry, but development of the necessary production technologies is, itself, a continuous process
GE Healthcare and Rockwell Collaborate on Next-GEN Bioprocess Automation
GE Healthcare and Rockwell Automation are collaborating on a next-generation bioprocess automation platform to help biopharmaceutical companies create flexible and scalable facilities of the future, with a focus on streamlined production technologies and adaptable...
AveXis to Acquire AstraZeneca Manufacturing Site in Longmont, CO
Novartis subsidiary AveXis plans to expand its gene therapy manufacturing capacity by agreeing to purchase AstraZeneca’s advanced biologics therapy manufacturing campus in Longmont, CO, for an undisclosed price.
AstraZeneca in January disclosed plans to close the...
A Shot in the Arm for Vaccine Manufacturing
Vaccine science has come a long way since the 18th century, when Edward Jenner used pus from a milkmaid’s sore to stop a child from catching smallpox.1 Since then, various vaccines have been developed,...
MilliporeSigma’s BioContinuum™ Platform
Biomanufacturing professionals are enthusiastic about continuous processing because they believe it will have a significant impact on how their customers bring therapies to market, delivering them to patients faster and more cost effectively.
MilliporeSigma officials...
