eBooks

In this Roundtable we have the CSO and director of research of a startup biotech company, Paros Bio, and experts from their partnering contract research organization (CRO), Charles River, discussing the specifics of their work and productive partnership. This discussion focuses on the emergence of Paros Bio, the science behind their PSEN1 program for Autosomal Dominant Alzheimer’s Disease (ADAD), and the perspectives from experts at both companies on the nature of their work and alliance.

This eBook, sponsored by Thermo Fisher Scientific, shows just some of the things that can be done with cryo-EM. We hope you will see how much the technique has matured, and how the microscopes themselves have become more intelligent, enabling users to focus on the science, instead of on the machine.

It’s essential to let science dispel such uncertainties. That’s why Cytiva presents evidence in this eBook that reveals an optimal cooling profile—avoiding too fast, and too slow.

When we battle disease, we need options other than brute force. We need precision weapons. And for many therapeutic applications, the precision weapons of choice are functionalized nanoparticles. This eBook, sponsored by Fortis Life Sciences, locates nanoparticles in the current order of battle. The battle in question is, of course, the battle between medical science and disease.

In response to the global COVID-19 pandemic, vaccine research and manufacturing processes have seen unprecedented advancements over a short timeframe. This eBook, sponsored by Sartorius, explores the latest methodologies and suggests alternative strategies in the development of future vaccines to fight the huge variety of infectious diseases.

Researchers push the boundaries of mRNA technology, creating market opportunities across a range of therapeutic modalities. Progress in each of these modalities depends on research advancements, examples of which make up the bulk of this eBook sponsored by Thermo Fisher.

This eBook, sponsored by Sartorius, explores how live-cell imaging and analysis technologies enable more objective and quantitative analysis, leading to deeper insights while supporting scientific research at scale. In general, these technologies are grounded in image segmentation, that is, the digitalized and automated recognition of individual cells or, rather, cell boundaries. 

This eBook, sponsored by Twist, offers a contemporary synthesis of CRISPR screening technologies for functional geneticists. In the chapters that follow, we’ll dive deeper into some of the most recent advances in the field, we’ll see how the technologies are being used today, and we’ll highlight CRISPR experiment design tips from leading experts in the field to help scientists see success with the next generation of functional genomic screens.

Stories in this eBook, sponsored by Thermo Fisher, may serve to remind readers that AAV advances seldom occur in isolation. They draw on varied technological developments, some rarefied. More important, they point to varied possibilities, none more essential than the  development of life-saving treatments.

In this eBook, sponsored by Isoplexis, we will cover recent cutting-edge research in cellular therapy, as well as several cases in which functional proteomics technology was used to optimize cell therapies at every stage of the development pipeline, filling critical gaps in cell therapy product quality assessment and predictive biomarker discovery.