Drug Discovery

Opiant Pharmaceuticals said this week it will launch a pivotal pharmacokinetics trial for its OPNT003 (nalmefene nasal spray) opioid overdose candidate in the second...

Furthering an incipient recognition of excipient effects, scientists based at Brigham and Women’s Hospital and MIT have shown that nearly all pills and capsules...

Scientists at the Howard Hughes Medical Institute are using an FDA-approved anti-smoking drug as a chemical switch that allowed them to turn specific populations...

As breast cancer progresses, tumor cell heterogeneity increases, metastatic colonization increases, and survival time decreases. At the same time, a new study from the...

Solid tumors are highly heterogeneous, and will exhibit very different distributions of specific cell types, such as immune system macrophages—which are involved in tumor...

Researchers at Columbia University's Mortimer B. Zuckerman Mind Brain Behavior Institute report that a prion-like protein, encoded by a gene called TIA1, helps the...

The hygiene hypothesis—or more recently dubbed microbiome depletion theory—is a supposition proposed in the late 1980s from the observation that children in larger family...

A 10-year study, involving veterans visiting the Richard L. Roudebush VA Medical Center and headed by Indiana University School of Medicine, have identified blood-based genetic markers of psychological stress that could help develop improved, earlier diagnostics for PTSD and other stress disorders, and offer up new leads for the development of drug or natural compound-based therapeutics.

Fujifilm has agreed to acquire Biogen’s large-scale biologics manufacturing site in Hillerød, Denmark, near Copenhagen for approximately $890 million cash, the companies said today,...

Merck & Co. plans to develop a new class of pain treatments using technology developed by Peter McNaughton, FMedSci, of King’s College London, through...