Vaccine Storage and Transport Transformed with Sugary Gel

Combining vaccines with sugars allows them to be stored and transported, removing the troublesome cold chain and enabling delivery to hard to reach areas. A multi-disciplinary team created a vaccine-storage method that suspends the vaccine in a tiny one-dose container filled with a sugar-gel combination that dries and can be reconstituted with water.

Human-Derived Brain Models

Human-derived neurons and brain organoids have revolutionized our ability to model brain development in a dish. In this "ASSAY and Drug Development Technologies" review, published by Mary Ann Liebert, Inc., the potential for human brain models to advance drug discovery for complex neuropsychiatric disorders is discussed.

Insulin-Producing Beta Cells Proliferate When the Brakes Are Off

Western-type diets that are laden with carbohydrates and fats put extra demand on the body’s pancreatic islets to produce enough insulin to control blood...

Citing “Strong Sales,” Pension Manager Buys Partial Keytruda Rights for $1.3B

A Canadian pension manager has shelled out $1.3 billion to acquire partial rights to Merck & Co.’s blockbuster cancer immunotherapy Keytruda® (pembrolizumab) from LifeArc—which...

Smart Insulin for Diabetes Therapy Could Protect against Hypoglycemia

A team of bioengineers at the University of California, Los Angeles (UCLA) has developed a form of "smart" insulin that can respond to changing...

Targeting Cancer Cells by Focusing on Protein-Protein Interaction

Scientists at the University of California, Riverside (UCR), say they have developed a new approach to targeting cancer cells that circumvents a challenge faced...

Genentech, Parvus Therapeutics Launch Up-to-$800M Autoimmune Collaboration

Genentech, a member of the Roche Group, today launched an up-to-$800 million partnership with Parvus Therapeutics to develop, manufacture, and commercialize new treatments for...

Thermo Fisher to Acquire API Plant in Cork, Ireland from GSK

Thermo Fisher Scientific said today it has agreed to acquire a drug substance manufacturing site in County Cork, Ireland, from GlaxoSmithKline (GSK) for €90...

CRISPR Reveals New Cancer Drug Targets through ID of Critical Gene...

Researchers study identified which gene fusions are critical for the growth of cancer cells and highlight a new drug target for multiple cancers. Their results suggested that while nearly 90% of the thousands of gene fusions analyzed are probably not important for cancer cell survival, some may have functional relevance and offer up new opportunities for drug repurposing or new drug development.

AI in Biopharma Slowed by Challenges Involving Data, Corporate Culture

Biopharmas are warming up to artificial intelligence (AI), but a series of challenges will need to be addressed before it becomes widely used by...

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