CRISPR Interference Tool Probes Antibiotic Resistance Genes

The rapid rise of antibiotic resistance represents a major global public health threat that has been estimated to endanger millions of lives and cost...

Pancreatic Cancer Immune Checkpoint Target Identified

The University of Texas MD Anderson Cancer Center-led team found that V-domain immunoglobulin suppressor of T cell activation (VISTA) is preferentially expressed at high levels in pancreatic cancer, when compared with melanoma tumors. Anti-VISTA antibodies may be an effective immunotherapeutic strategy for patients with pancreatic cancer.

Chemo Overflows Sopped Up by Vein-Lodged Sponges

Toxic spills aren’t limited to the environment. They happen inside the body, too, whenever chemotherapeutics slosh beyond the tissues they are meant to target,...

Taking Aim at Target ID and Validation

In The Hunger Games, Katniss Everdeen shocked the distracted gamemakers seated above her by shooting an arrow and blasting an apple out of the...

Building Better Mice for Cancer Drug Discovery and Development

Immunotherapy developers are beating a path to humanized preclinical models.

Precision Medicine: Getting Oncology Drug Development Right

With the U.S. Food and Drug Administration approving an increasing number of targeted therapies and hundreds more in late-stage oncology pipelines close behind, pharmaceutical...

Neuromuscular Platforms for Drug Discovery

Sponsored Content Brought to you by   Mouse models, pioneered by The Jackson Laboratory (JAX), the renowned research institute headquartered in Bar Harbor, ME, provide a...

Using Powered Cohorts to Speed Drug Discovery and Development

WuXi NextCODE provides comprehensive sequencing and advanced analytics to enable discovery of novel drug targets, reveal complex biological pathways, and identify biomarkers to enhance...

Catalent Invests $200M in Fast-Growing Biologics Manufacturing Business

Catalent says the $200 million it will spend over three years to expand drug substance manufacturing capacity and drug product fill/finish capacity in Bloomington,...

Hospitalized Patients Can Safely Receive Flu Vaccine

Hospitalized patients who received the flu vaccine had no increased risk of outpatient visits or hospital readmission within seven days of discharge.

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