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In the latest issue of GEN, gene drive technology is advancing in preparation for eventual deployment against mosquito populations. A new documentary on CRISPR technology focuses on potential game-changing applications such as the elimination of monogenic disorders like sickle cell disease. Challenges of scale are propelling bioreactor design toward single use, user-friendliness, and efficiency. This month’s A-List features 25 up-and-coming gene therapies.

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