Volume 44, Issue No. 5, May 2024
The May issue of GEN has a hidden theme: technologies are emerging to shore up our immune defenses. What’s so hidden about that? Well, the technologies are quite varied: multispecific antibodies, cell therapies, and next-generation vaccines. So, it’s easy to miss the big picture, which is that the immune system is both intricate and finely balanced—as deserving, in its own way, of the respect accorded celestial mechanics, the subtleties of which inspired the ancients to coin the term musica universalis, which refers to the unheard music of harmony and equilibrium. Now it’s the immune system’s turn. Should the immune system become discordant or disequilibrated by the operations of a disease process, it needn’t succumb to chaos. Interventions are possible. For example, when cancer intrudes, therapeutic cells can restore order. If only rogue planets could be so easily counterbalanced.