GEN Magazine

Volume 44, Issue No. 5, May 2024

May 2024 issue cover

The May issue of GEN has a hidden theme: technologies are emerging to shore up our immune defenses. What’s so hidden about that? Well, the technologies are quite varied: multispecific antibodies, cell therapies, and next-generation vaccines. So, it’s easy to miss the big picture, which is that the immune system is both intricate and finely balanced—as deserving, in its own way, of the respect accorded celestial mechanics, the subtleties of which inspired the ancients to coin the term musica universalis, which refers to the unheard music of harmony and equilibrium. Now it’s the immune system’s turn. Should the immune system become discordant or disequilibrated by the operations of a disease process, it needn’t succumb to chaos. Interventions are possible. For example, when cancer intrudes, therapeutic cells can restore order. If only rogue planets could be so easily counterbalanced.

Website Content from This Issue

Multispecific Antibodies Come to Grips with Manifold Targets

Bispecific antibody in action

Vaccine Developers Leverage mRNA and Other Powerful Technologies

Emergex Vaccines research

In Vivo Gene Editing Grants Access to Medical Treasures

Adeno-associated viruses, illustration

Proteomics in Portland: A Report from the U.S. HUPO Meeting

US HUPO 2024

Rise of Automation in Mass Spectrometry–Based Proteomics

Opentrons feature image

Cell Therapy Manufacturing: Time to Move Fast

Cell Therapy lab picture

Protein Microparticles Turn Infusions into Injectables

Elektrofi Seaport Lab

Top 10 Best-Selling Cell and Gene Therapies

cell and gene therapy

Bad Facts Make for Horrible Health Policy

Advanced In Vitro Screening of New Drugs for Proarrhythmic Activity

Organoid-Immune Co-Culture Models for Cancer Research

Sino Biological May 2024 sponsored content Graphic

Addressing Unmet Needs for Cryopreservation in Cell Therapies

Cryopreservation of test tube on liquid nitrogen, a liquid nitrogen bank containing sperm and eggs cryosamples

The Emerging Role of ssDNA in Gene Therapy

Moligo mosic figure

Transforming Genomics Workflows with Automated Liquid Handling

May 2024 SPT Labtech sponsored content feature image

The Crucial Role of Organ-on-a-Chip Technology in Understanding Mechanistic Toxicity

May 2024 CN-BIO sponsored content feature image

What Lies Ahead? Shaping the Future of Cell and Gene Therapy

DNA Helix

Humanized Mice in Advancing Vaccine Research for Cancer and Infectious Diseases

May 2024 Jackson Labs sponsored content feature image

Diagnostic Analyzer

Microcarrier Platform

Line Sterilizer

Next-Generation Ultramicrotome

Process Flexibility in Viral Vector Manufacturing

Fully Automated Sample Handling

Universal Vaccine Strategy Boosts Body’s RNAi Response to Viruses

Doctor giving baby injection in doctor's office

HIV-Free Hopes Raised by Reservoir-Targeting VLPs


Culprit behind Psoriasis Revealed

A close-up of bad psoriasis on a person's arm

StockWatch: CDMOs Tumble as Congress Takes Aim at Chinese Biotechs

mRNA Therapeutics May Act Longer If Given Multiple Tails

Oral Bacterium Migrates to Gut, Helps Colorectal Tumors Grow

A microscope image shows a human colorectal cancer tumor with Fusobacterium nucleatum stained in a red-purple color. The bacterium is commonly found in people’s mouths. Fred Hutch researchers have found a specific subtype of F. nucleatum that can move to the gut, where it helps colorectal cancer grow.