Both Obese and Anorexic Women Suffer Low Levels of Mood-Enhancing Hormone

Scientists have found that low levels of the neuroactive steroid allopregnanolone correlate with anxiety and depression in women with anorexia nervosa or obesity

FDA Approves Cervical-Cancer-Related HPV Test

An FDA-approved test for the human papilloma virus (HPV) can detect the genotypes likely to cause cervical cancer in women

Insys Recommits to “High Ethical Standards” After Five Doctors Indicted on...

U.S. Attorney’s Office for the Southern District of New York and FBI allege that the doctors accepted fees for sham educational programs in exchange for prescribing millions of dollars’ worth of Subsys®

Therapeutic Vaccine Suppresses Peanut Allergies

Researchers aim to develop a new immunotherapy that could alter the immune reactions to food.

Shire, Takeda Come to Terms on $62B Acquisition Deal

Combined company plans to complement Takeda’s areas of therapeutic focus—namely oncology, gastroenterology, and neuroscience therapeutic areas plus vaccines—with Shire’s strengths in rare diseases and other areas

Speeding Drug Development with Clinical Trials in a Dish

A new perspective about clinical trials in a dish (CTiD), a novel strategy that bridges preclinical testing and clinical trials

Novartis Licenses MorphoSys/Galapagos Atopic Dermatitis Candidate MOR106 for $1.1B+

Novartis also agreed to explore the potential of MOR106 in indications other than atopic dermatitis, where MorphoSys and Galapagos plan to conduct additional trials to support development of the candidate.

HIV-AIDS Vaccine

Significant progress is being made toward the development of an effective HIV-AIDS vaccine. In autumn 2009, a collaborative effort between the Ministry of Health in Thailand, the U.S. Military, and the U.S. National Institute of Allergy and Infectious Disease announced the first encouraging results from an efficacy trial—31% prevention of infection in a 16,402-person community-based trial in Thailand. With this encouraging news in the background, several companies are working toward an AIDS vaccine. So, when do you think one will be approved in the U.S.?

Bayer Axing 12,000 Jobs, Closing Factor VIII Plant in Restructuring

Bayer said today it will eliminate about 12,000 jobs worldwide by the end of 2021—approximately 10% of its total workforce—in a restructuring designed to...

Able-Handed Drugs Could Push GPCR Buttons, Say Conformation Mappers

One does not bang on the drug target known as the G-protein-coupled receptor (GPCR) as though it were a drum. Neither does one play...

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