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About five million people in the United States alone live with traumatic brain injuries (TBIs). These injuries can quadruple the risk of developing Alzheimer’s disease, and other dementias, and increase the likelihood of developing neurodegenerative diseases such as amyotrophic lateral sclerosis. Rodent models of TBI have clarified some aspects of these injuries; however, most treatment approaches have had limited success because some of the details of the underlying mechanisms are still unclear.  

In this GEN webinar, Justin Ichida, PhD, an expert in stem cell biology and regenerative medicine at the Keck School of Medicine at the University of Southern California discusses using organoids to clear up the causes of neuronal damage following TBIs and ways of mitigating injury risks. During the webinar, he’ll present results from a study that used lab-grown human brain organoid models to parse the genetic mechanisms involved in TBIs and explore their connection to neurodegenerative disorders. He’ll also discuss possible methods of treating brain injuries that were identified by the study. 

A live Q&A session followed the presentation, offering a chance to pose questions to our expert panelist.

Justin Ichida, PhD
Justin Ichida, PhD
Associate Professor of Stem Cell Biology and Regenerative Medicine
Keck School of Medicine, University of Southern California