Advancing Direct Enzyme Delivery for Therapeutic Genome Editing In Vivo
Sponsored by: Aldevron and SynthegoIn this GEN webinar, sponsored by Aldevron and Synthego, we will hear how the Wilson lab works to advance this approach by performing molecular engineering, giving CRISPR enzymes the properties necessary for safe, efficient, and accessible delivery in a clinical setting. These efforts will enable in vivo delivery of CRISPR enzymes, including hard-to-deliver tools such as base editors and prime editors.
Redesigning CHO: The New Frontier in Bioprocessing?
Sponsor: Horizon DiscoveryIn this GEN webinar, sponsored by Horizon, we will hear about the gene-editing tools and options available at Horizon Discovery to customize the CHO expression host for both research and commercial use to suit specific needs during discovery, development, and protein production.
Solving Metadata Management from Sample Provenance through Omics
Sponsored by: SnthesisIn this GEN Webinar, sponsored by Snthesis, we will hear about the challenges facing research teams as they work to curate large omics data sets in preparation for analysis. We will then explore modern strategies and technical approaches that can dramatically simplify and improve the process.
Creating the Future of Cell and Gene Therapies
Sponsored by: PerkinElmerIn this GEN webinar, sponsored by PerkinElmer, our distinguished presenters will provide perspectives on how the gene therapy field ought to evolve. From the early vector systems, which often represented replicating viruses, to the recent sophisticated engineering of targeted virus driven cell and gene therapies that have demonstrated clinical benefits and gained FDA approval for multiple diseases.
The Secret to Improving the Therapeutic Index of Antibody Drug Conjugates
Sponsored by: 3DS Dassault Systemes
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Broadcast Date: February 5, 2019
Time: 8:00 am PT, 11:00 am ET, 17:00 CET
Antibody-drug conjugates (ADCs) were initially developed to provide a selective targeting...
Preventing Dementia through a Virtual Twin Brain
Sponsor: Dassault SystèmesGEN's on demand webinar, sponsored by Dassault Systèmes, discusses the current state of The Living Brain Project and how it is being applied to traumatic brain injury, neuromodulation, neurodegenerative disease progression, and drug delivery through cerebrospinal fluid.
Streamlined Formulation of Enzyme Products
Sponsored by: Unchained Labs
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Broadcast Date: February 26, 2019
Time: 8:00 am PT, 11:00 am ET, 17:00 CET
There are two complementary paths to creating a stable enzyme formulation....
How to Decrease Long Read Sequencing Sample QC Time by 10-Fold
Sponsored by: AgilentThis presentation will show how low concentrated samples, as well as libraries prepared for long read sequencing benefit from QC, performed with the Femto Pulse.
Association Rate Constant: The Unsung Hero of Drug Discovery Kinetics
Sponsor: CisbioWhile the importance of ligand-receptor binding kinetics on drug action is becoming well established, focus to date has been almost entirely on the role of the dissociation constant on drug efficacy and duration of action. The association rate constant, in contrast, has been largely overlooked, with many investigators still considering it diffusion-limited and equivalent across a compound series. This GEN webinar aims to remedy that by turning the spotlight onto the undervalued and oft-ignored association rate constant.
Recent Advances and the Future of Antibody Engineering
Sponsor: Bio-techneIn this GEN webinar, we will hear from Danica Stanimirovic MD, PhD, and Danica Stanimirovic MD, PhD, wto leading scientists who will describe their current antibody engineering research projects and the therapeutic potential they hold.
Pancreatic Cancer Therapeutic Target Visualized Using In Situ Hybridization
Sponsor: Advanced Cell DiagnosticsIn this GEN webinar sponsored by Advanced Cell Diagnostics, we will hear about new PDAC research showing that the cytokine leukemia inhibitory factor (LIF) key paracrine factor from activated pancreatic stellate cells acting on cancer cells.
Measuring Multivalent Interactions: Uncovering the Secrets of Virus Binding Strategies
Sponsor: NanotemperIn this GEN webinar, we will learn from Dr. Daniel Lauster, who, when faced with many of the challenges described above, utilized MicroScale Thermophoresis (MST) to measure the interaction between more than 100 novel non-toxic multivalent nanoparticle-conjugates and intact IAV in solution with as little as nanomoles of nanoparticles. Additionally, we will hear from Dr. Matthias Molnar how MST is becoming scientists’ first choice for the characterization of molecular interactions thanks to its flexible throughput, low sample consumption, and measurements in solution or in close to native conditions.
Mind the Yap! Single-Cell Transcriptomes Reveal Drivers of Intestinal Regeneration
Sponsor: Advanced Cell DiagnosticsIn this GEN webinar, we will hear about recent findings implicating the Hippo effector, Yap, as a driver of a novel damaged-induced intestinal stem cell population.
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