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Advancing Direct Enzyme Delivery for Therapeutic Genome Editing In Vivo

In this GEN webinar, sponsored by Aldevron and Synthego, we will hear how the Wilson lab works to advance this approach by performing molecular engineering, giving CRISPR enzymes the properties necessary for safe, efficient, and accessible delivery in a clinical setting. These efforts will enable in vivo delivery of CRISPR enzymes, including hard-to-deliver tools such as base editors and prime editors.

Redesigning CHO: The New Frontier in Bioprocessing?

In this GEN webinar, sponsored by Horizon, we will hear about the gene-editing tools and options available at Horizon Discovery to customize the CHO expression host for both research and commercial use to suit specific needs during discovery, development, and protein production.

Solving Metadata Management from Sample Provenance through Omics

In this GEN Webinar, sponsored by Snthesis, we will hear about the challenges facing research teams as they work to curate large omics data sets in preparation for analysis. We will then explore modern strategies and technical approaches that can dramatically simplify and improve the process.

Creating the Future of Cell and Gene Therapies

In this GEN webinar, sponsored by PerkinElmer, our distinguished presenters will provide perspectives on how the gene therapy field ought to evolve. From the early vector systems, which often represented replicating viruses, to the recent sophisticated engineering of targeted virus driven cell and gene therapies that have demonstrated clinical benefits and gained FDA approval for multiple diseases.

The Secret to Improving the Therapeutic Index of Antibody Drug Conjugates

REGISTER NOW Broadcast Date: February 5, 2019 Time: 8:00 am PT, 11:00 am ET, 17:00 CET Antibody-drug conjugates (ADCs) were initially developed to provide a selective targeting...

Preventing Dementia through a Virtual Twin Brain

GEN's on demand webinar, sponsored by Dassault Systèmes, discusses the current state of The Living Brain Project and how it is being applied to traumatic brain injury, neuromodulation, neurodegenerative disease progression, and drug delivery through cerebrospinal fluid.

Streamlined Formulation of Enzyme Products

REGISTER NOW Broadcast Date: February 26, 2019 Time: 8:00 am PT, 11:00 am ET, 17:00 CET There are two complementary paths to creating a stable enzyme formulation....

How to Decrease Long Read Sequencing Sample QC Time by 10-Fold

This presentation will show how low concentrated samples, as well as libraries prepared for long read sequencing benefit from QC, performed with the Femto Pulse.

Association Rate Constant: The Unsung Hero of Drug Discovery Kinetics

While the importance of ligand-receptor binding kinetics on drug action is becoming well established, focus to date has been almost entirely on the role of the dissociation constant on drug efficacy and duration of action. The association rate constant, in contrast, has been largely overlooked, with many investigators still considering it diffusion-limited and equivalent across a compound series. This GEN webinar aims to remedy that by turning the spotlight onto the undervalued and oft-ignored association rate constant.

Recent Advances and the Future of Antibody Engineering

In this GEN webinar, we will hear from Danica Stanimirovic MD, PhD, and Danica Stanimirovic MD, PhD, wto leading scientists who will describe their current antibody engineering research projects and the therapeutic potential they hold.

Pancreatic Cancer Therapeutic Target Visualized Using In Situ Hybridization

In this GEN webinar sponsored by Advanced Cell Diagnostics, we will hear about new PDAC research showing that the cytokine leukemia inhibitory factor (LIF) key paracrine factor from activated pancreatic stellate cells acting on cancer cells.

Measuring Multivalent Interactions: Uncovering the Secrets of Virus Binding Strategies

In this GEN webinar, we will learn from Dr. Daniel Lauster, who, when faced with many of the challenges described above, utilized MicroScale Thermophoresis (MST) to measure the interaction between more than 100 novel non-toxic multivalent nanoparticle-conjugates and intact IAV in solution with as little as nanomoles of nanoparticles. Additionally, we will hear from Dr. Matthias Molnar how MST is becoming scientists’ first choice for the characterization of molecular interactions thanks to its flexible throughput, low sample consumption, and measurements in solution or in close to native conditions.

Mind the Yap! Single-Cell Transcriptomes Reveal Drivers of Intestinal Regeneration

In this GEN webinar, we will hear about recent findings implicating the Hippo effector, Yap, as a driver of a novel damaged-induced intestinal stem cell population.

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