Human induced pluripotent stem cell (iPSC)-derived organoids combine the ability to generate diverse cell types with the retention of parental genetic backgrounds, providing opportunities to investigate human development, disease mechanisms, and individual differences in therapeutic responses. These models capture aspects of complex tissue architecture and multicellular interactions within a more physiologically relevant spatial environment. Over the past two decades, advances in stem cell reprogramming, directed differentiation, and three-dimensional culturing techniques have enabled the development of organoid models for the brain, retina, heart, lung, intestine, liver, pancreas, kidney, and many more.

In this GEN webinar, our expert speaker, Arati Naveen, PhD, will trace the foundational discoveries that shaped organoid technology as a new approach methodology (NAM), while highlighting pioneering contributions and contemporary advances. This webinar will examine the ways in which the challenges of tissue maturation, vascularization, reproducibility, and scalability, are being addressed. One example explored is harnessing microgravity to strengthen organoid performance and support the broader adoption as NAMs.

A live Q&A session will follow the presentation offering you the chance to pose questions to our expert panelist.

Produced with support from: