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This GEN webinar, sponsored by Agilent Genohm, will focus on two key areas: how implementing a sample and workflow management system such as SLIMS can have a major impact on a biobank’s efficiency, and how integrating these sample management systems with other technologies used by biobanks, such as freezers and readers for tracking samples, can create even greater value in the solutions biobanks have to offer.
The FDA has placed a second clinical hold in as many years on Solid Biosciences’ Phase I/II trial for its lead candidate, the Duchenne muscular dystrophy (DMD) gene therapy SGT-001, sending the company’s shares plunging about 70%.
In this sponsored GEN webinar, we will hear how Chromium Connect from 10x Genomics was designed to simplify single-cell library prep workflows and increase laboratory productivity. Additionally, the 10x-pert presenters will demonstrate how the new automated system will enable walkaway convenience while generating consistent single-cell gene expression results.
MRI scan of brain
Neuroengineers at Columbia University report evidence suggesting that individual neurons in the human brain are involved in spatial memory, such as recalling the prior location of an object. The team measured the activity of neurons in epilepsy patients with already implanted electrodes, who carried out a virtual reality task. They found it was possible to decode the specific memory a patient was targeting, based on the activity of these individual neurons.
The liquid biopsy company, Lexent Bio, is currently developing a test that will measure a cancer's response to treatment. They hope that the test, Confera, will be made available next year as a laboratory developed test (LDT) with a distributable in vitro diagnostic (IVD) kit to follow. Lexent recently announced a nonexclusive partnership with Illumina to develop the kits.
With traditional clinical methods, infections caused by flesh-eating bacteria may be classified as a monomicrobial even when they are, in fact, polymicrobial. Metagenomic methods, however, can clarify the roles of cooperating strains. Two strains, a new metagenomic study shows, are deadly together because one breaks down muscle tissue and allows the other to spread to the bloodstream or organs.
Celgene and Acceleron Pharma have won a first-in-class FDA approval for Reblozyl® (luspatercept-aamt), an erythroid maturation agent that has won the agency’s first authorization to treat anemia in adults with beta thalassemia who require regular red blood cell (RBC) transfusions.
CRISPR
Scientists at the City of Hope believe they may have found a way to sharpen the fastest, cheapest, and most accurate gene editing technique, CRISPR-Cas9, so that it can more successfully cut out undesirable genetic information.
Carnegie Mellon University scientists carried out a comprehensive examination of neural development in boys and girls, which demonstrated that neural functioning is similar in both sexes, and effectively refuted the myth that girls have poorer aptitude for math than boys. The researchers hope the results will help to recalibrate expectations of what children can achieve in mathematics.
eGenesis, a developer of human-compatible organs created through its own multiplexed gene editing platform, has raised $100 million in Series B financing. The company's co-founders include George Church, PhD, of Harvard Medical School.

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