Lysis and Hypotonic Sonication Buffers for ChIP Assays

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Offering disruption of cytoplasmic and nuclear membranes, Porvair Sciences Chromatrap® buffer chemistries were designed for sonication and enzymatic shearing. Chromatrap lysis and hypotonic buffers are reagents that can be used as a first step in isolating chromatin from your sample. Porvair Sciences optimized Chromatrap hypotonic buffer composition to ensure effective lysis of cell membranes to aid in releasing nuclei material from a wide range of varied species. The company claims it is formulated for difficult-to-lyse cell types and tissues and allows researchers to explore and understand the underlying processes and mechanisms that drive biological organisms.

Porvair Sciences

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