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Biologics manufacturers are under increasing pressure to reduce production costs. This is a key driver for moving to continuous processing, which maximizes productivity while minimizing footprint. Since its inception, Just-Evotec Biologics, Inc. has explored the use of continuous processing to reduce the cost of manufacturing biologics. One part of Just-Evotec Biologics’ strategy is a modular facility design that supports seamless scaling between early and late-phase productions. Another cornerstone is the process itself: Continuously perfused bioreactors are coupled with a multi-column capture step and alternating two-tank viral inactivation, enabling high mass output and enhanced product quality. The coupling of these downstream steps directly to the perfused bioreactor effluent enables efficient liquid handling of large volumes with minimal operator intervention.
In this GEN webinar, our speaker, Andrew Wagner, PhD, delves into Just-Evotec Biologics’ strategy for continuous processing. Discover their approach, featuring a modular facility design and an integrated, continuous purification process, confirming that today’s technology can deliver highly productive processes.
Learning Objectives:
1. Learn how multi-column continuous capture improves efficiency and reduces resin utilization
2. Discover how coupling viral inactivation with multi-column capture streamlines liquid handling
3. Understand the challenges to achieving fully end-to-end continuous manufacturing
A live Q&A session followed the presentation, offering a chance to pose questions to our expert panelist.
Senior Scientist II Purification Process Design
Just-Evotech Biologics
Webinar produced with support from:
