Strong Points: Extensive documentation and tutorials for the database; search function is easy to use.
Mcule makes the discovery phase of drug discovery easier than ever. The website allows users to input chemical compounds and search an extensive database for matches. Users can adjust their search parameters to include compounds that are purchasable or in stock, making it easy to buy and ship compounds of interest immediately. There are several hit identification tools available, including diversity selection and property filters. Additionally, optimization is made easy by models that check for scaffold docking and potential toxicity, and users can build their own screening workflows and libraries. The Mcule website contains extensive and easy to follow documentation for all available features on the site and includes tutorial videos for new users. Mcule is a great drug discovery resource where users can search for hits, optimize parameters, and order compounds of interest all in one place.