January 15, 2017 (Vol. 37, No. 2)
URL:
http://www.addgene.org/crispr
Rating:
Strong Points: Great educational resources and plasmids
Weak Points: None
Summary:
CRISPR-Cas9 technology is officially here to stay, and it indeed appears to be the genome-editing method of the foreseeable future. While Addgene is known for its vast plasmid repository—including a number of plasmids for CRISPR-Cas9 genome-editing that span eight different model organisms—what researchers may not know is that the Addgene website also contains a number of useful educational resources to help researchers new to the technique get up-and-running. These resources include the CRISPR guide containing background information on the technique, a list of online CRISPR resources such as tools for data analysis or guide RNA design, and a collection of protocols. Site visitors who want all of the information in one place can also download the free “CRISPR 101” eBook after providing basic contact information.