SARS-CoV-2 Variants Develop in Chronic, Immunosuppressed Patients

New research points to where SARS-CoV-2 variants originate. The study suggests that chronic infections in patients who are immunosuppressed lead to highly mutated variants that bear multiple antibody-resistant mutations. The virus’ ability to survive and reproduce in the immunosuppressed patient’s body—without restriction—leads to the evolution of many variants. While many different variants are formed, they are at low risk for rapid spread.