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With close to four percent of the global population being affected by the more than 80 diverse types of autoimmune diseases, it is imperative that we gain as much knowledge on the underlying biology of these disorders. The advent of genotyping and whole-genome sequencing technologies has allowed more omics data to become available for integrative analysis and provides an opportunity to ask new questions about these diseases. The future of precision medicine for autoimmune disorders lies in our ability to leverage the vast amounts of omic data generated to develop new therapies and make better decisions about treatments for afflicted patients.

In this GEN Keynote webinar, our distinguished guest, Dr. Marina Sirota, associate professor at UCSF, will describe how her laboratory is leveraging the genetic data across phenotypes to elucidate the genetic architecture of disease with a particular interest in autoimmune disorders. Moreover, Dr. Sirota will explain how she has applied next-generation sequencing technologies to better understand the immune system’s role in disease and illustrate her laboratory’s ongoing projects in systemic lupus erythematosus, rheumatoid arthritis, and dermatomyositis—which has recently been extended to single-cell analysis.

A live Q&A session followed the presentation, offering a chance to pose questions to our expert panelist.

Marina Sirota, PhD
Marina Sirota, PhD
Associate Professor
Bakar Computational Health Sciences Inst.
University of California, San Francisco

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