Home Sequencing Next-Generation Sequencing Fast and Flexible: Singular’s G4 Takes Aim at Illumina’s Sequencing Superiority

Singular Genomics G4 — Singular Genomics Systems says the G4 platform it launched this month will surmount the challenge posed by the longtime leader in next-generation sequencing, by competing with two of Illumina’s systems successfully enough to draw its own customers looking for an alternative. [Singular Genomics]

Fast and Flexible: Singular’s G4 Takes Aim at Illumina’s Sequencing Superiority

CEO Andrew Spaventa says the newly released G4, positioned between NextSeq and NovaSeq, lays claim to the title of the world’s most powerful benchtop sequencer, with reduced run times and higher data output.

By Alex Philippidis

January 3, 2022

Singular Genomics Systems says the G4 platform it launched this month will surmount the challenge posed by the longtime leader in next-generation sequencing, by competing with two of Illumina’s systems successfully enough to draw its own customers looking for an alternative. [Singular Genomics]

Singular asserts that the G4 lives up to the company’s name in several ways, starting with its power output ranging from of 15 to 400 gigabases (Gb)—delivering at the high end up to three times more data output per hour than other benchtop instruments—with run times for typical NGS applications starting at about five hours, up to between 16 and 19 hours for four complete human genomes. Singular expects that will help G4 to effectively position itself between Illumina’s NextSeq and NovaSeq sequencing systems . . .