RNA technology has had its own Big Bang event. It occurred just a couple of years ago when, seemingly out of nothing, the mRNA-based COVID-19 vaccines appeared. Well, they only seemed to come out of nothing. The underlying technology for the vaccines had been in development for decades. Nonetheless, under the pressure of the COVID-19 pandemic, the development of mRNA-based vaccines was greatly accelerated. Today, everything in the RNA technology universe is expanding. Production technologies such as in vitro transcription are maturing, RNA modalities beyond mRNA are emerging, and delivery vehicles are proliferating. Most important: like the cosmos, the RNA universe is becoming more interesting. Whereas the cosmos forms galaxies, the RNA universe gives rise to myriad applications. These include vaccines against varied diseases, and therapeutics for conditions from enzyme deficiencies to cancer.
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