Rubicon Genomics’ preanalytical platform products will incorporate ZyGEM’s advanced enzymatic nucleic acid extraction technology. The companies’ agreement will initially focus on diagnostic single-cell whole-genome amplification kits but in the future may be expanded to include products for broader research and diagnostic applications.


Rubicon will soon launch its PicoPlex™ kits that integrate ZyGEM’s DNA extraction technology, which uses a thermophilic enzyme to extract DNA from samples using a single closed-tube system. The product targets the preimplantation genetic diagnostic and cancer diagnostic markets, which require rapid, reproducible amplification to profile patient genotypes, karyotypes, and mutations. PicoPlex will enable reference labs to begin qPCR, microarray, or sequencing analysis less than three hours after collecting patient cells, according to Rubicon.

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