Besides an upfront payment, the UMMS and the CIW will obtain annual maintenance and milestone fees as well as royalties.



Oxford BioMedica licensed certain RNAi patents from the University of Massachusetts Medical School (UMMS) and the Carnegie Institution of Washington (CIW). The company plans to pursue novel applications of RNAi using its lentiviral vector delivery technology.


The company obtained nonexclusive rights as well as certain exclusive rights for human gene therapy applications of RNAi using lentiviral vectors. In exchange, Oxford BioMedica will make an upfront payment as well as annual maintenance and milestone fees and royalties.


“As the medical school looks toward the convergence of RNAi, gene therapy, and cellular therapy, including stem cells as medical treatments, the potential drug development opportunities presented by Oxford’s lentiviral vector delivery technology is intriguing to us,” comments James P. McNamara, Ph.D., executive director of the office of technology management of the UMMS. “We have structured these license agreements to help the company pursue novel applications of RNA interference based on their established broad IP in the lentiviral vector delivery space.”








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