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The interest in the use of organoids to model human development in health and disease is at an all-time high. Recently, a team from the U.K. demonstrated that progenitor cells from amniotic fluid, referred to as tissue specific stem cells (and are distinct from pluripotent stem cells), can form fetal organoids. The researchers successfully developed organoids of multiple different tissue types (small intestine, kidney, and lung) from the cells collected from the amniotic fluid samples, without accessing fetal tissue or termination of the pregnancy. 

In this GEN keynote webinar, Mattia Gerli, PhD, and Paolo De Coppi, MD, (University College London, Institute of Child Health) will reveal how their team achieved this landmark in organoid research. De Coppi, a pediatric surgeon at Great Ormond Street Hospital and head of stem cells and regenerative medicine at the University College London, focuses on congenital malformation. Together with Gerli, he will offer perspectives into how these organoids will further our understanding of development during later-stage pregnancies and advance research into congenital anomalies.

A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert panelists.

Paolo De Coppi
Paolo De Coppi, MD
Pediatric Surgeon and Head of Stem Cells and Regenerative Medicine
UCL Great Ormond Street Institute of Child Health
Mattia Gerli
Mattia Gerli, PhD
Lecturer in Stem Cell Science & Biomaterials
Faculty of Medical Sciences at the UCL