Udayabagya (Bud) Halim, PhD
Senior Marketing Analyst
Waters | Wyatt Technology
Karessa White, PhD
Senior Market Applications Scientist
Waters
- Time:
Aggregation and the formation of oligomers and high molecular weight species (HMWS) remain critical challenges in biotherapeutic development. Left unchecked, they can impact product efficacy, safety, and regulatory approval. To that end, regulators suggest the use of orthogonal techniques that can detect and characterize particles of different sizes.
In this GEN webinar, our expert speakers, Karessa White, PhD, and Bud Halim, PhD, will present a systematic approach for identifying oligomers, HMWs, and aggregates in biotherapeutics manufacturing. You will learn about a high-throughput workflow integrating dynamic light scattering (DLS) and background membrane imaging (BMI) to characterize particles across size regimes, from nanometers to sub-visible and beyond. Key takeaways from the webinar include:
- How oligomers and HMWs compromise stability, safety, and regulatory approval in today’s biologics
- How orthogonal detection methods deliver complementary quantitative and qualitative insights into stability
- Practical strategies for monitoring aggregation from early formulation through development and manufacturing
A live Q&A session will follow the presentations, offering you a chance to pose questions to our expert panelists.
Produced with support from:
