LY-CoV1404 entered the Phase II BLAZE-4 trial (NCT04634409), which was expanded to study the antibody’s safety and effectiveness in patients with mild-to-moderate COVID-19, alone and in several combinations—including one with bamlanivimab, and one with another antibody that Lilly is developing with Shanghai Junshi Biosciences, etesevimab (LY-CoV016 or JS-16 . . .
AbCellera, Lilly Advance Next-Generation Antibody vs. COVID-19
LY-CoV1404 enters the clinic after binding, neutralizing SARS-CoV-2 variants in preclinical study
AbCellera and Eli Lilly have advanced into the clinic a second co-developed antibody designed to fight COVID-19—as well as several variants of the virus that have shown resistance to the companies’ first co-developed antibody, bamlanivimab (LY-CoV555). [AbCellera]