October 1, 2011 (Vol. 31, No. 17)

Benchtop Bioreactor Solutions for Optimal Bioprocessing

Increasing process complexity coupled with rising cost pressures and rapidly evolving regulatory requirements make today’s process-development efforts a special challenge. The pressure of achieving faster time to market for new and innovative biopharmaceuticals had led to the need to optimize every element of the total development workflow.

Precision cultivation and fermentation systems, sophisticated analytical devices, and higher throughput enable significant opportunities for optimization of existing processes or the development and introduction of entirely new bioprocess methodologies.

DASGIP Parallel Bioreactor Systems and software solutions enable streamlined process development at the benchtop scale in accordance with QbD standards and industry accepted best practices.

About the Company

DASGIP has been an industry-leading supplier of benchtop bioreactor solutions for the biotech, pharma, and chemical industries as well as academia and research institutions since 1991. Our Parallel Bioreactor Systems for the cultivation of microbial, plant, animal, and human cells utilize industry-standard benchtop glass and single-use bioreactors. DASGIP’s best in class configurable control systems and state-of-the-art bioprocess analyzers deliver unparalleled functionality coupled with user-friendly design for optimal bioprocessing. Our proven solutions for interconnectivity to third party bioprocess analyzers, supervisory control systems, and DoE tools, combined with our best-in-class control systems, enable migration strategies for optimization of legacy benchtop bioreactor equipment.

The outstanding DASGIP bioprocess solutions support QbD-driven process development. A team of more than 70 in-house experts contribute to the ongoing success of the company with a compound five years annual growth rate of about 25%. Excellent products and outstanding global service are our commitment to support the success of each customer. DASGIP is headquartered in Jülich (Germany) and has operations throughout Europe, North America, and Asia.

Markets Served

DASGIP customers are from the biotechnological, pharmaceutical, and chemical industries as well as from academia and research institutes. Process engineers and scientists use DASGIP Parallel Bioreactor Systems and software solutions for the cultivation of their cells to benefit from increased productivity, high reproducibility, and ease of scale-up.

DASGIP Parallel Bioreactor Systems and software solutions are designed for:

  • characterization and selection of cell lines and strains,
  • process development and optimization, and
  • small-scale manufacturing of proteins and biomass.

Capabilities

DASGIP Parallel Bioreactor Systems combine the convenience of simple systems such as flasks and shakers with the benefits of bioreactors: The systems’ small working volumes allow high experimental throughput with minimal input while precision and automated control offer highly optimized scalable processes.

Based on our modular design, an assortment of bioreactors in various sizes can be operated in parallel. Integrated modules provide independent control of pH, dissolved oxygen, temperature, agitation, media and gas supply, as well as optical density and off-gas analysis. The compact size of the DASGIP Bioreactor Systems ensures they easily fit into any laboratory, making them well suited for environments where space is at a premium.

DASGIP provides a set of software solutions for optimal bioprocessing at benchtop scale. Every DASGIP Parallel Bioreactor System features real-time process control, integrated process historian, and batch and recipe management. In addition, DASGIP provides solutions for interconnectivity of bioreactor systems to third party bioprocess analyzers and supervisory control systems as well as DoE tools and migration strategies, which enable optimization of legacy benchtop bioreactor equipment. The result being that DASGIP bioprocess solutions enable QbD-driven process development.

DASGIP

Rudolf-Schulten-Str. 5

52428 Jülich, Germany

Phone +49 (0)2461 980 0

Website www.dasgip.de

Date Founded 1991

Number of Employees 70

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