Leading the Way in Life Science Technologies

GEN Exclusives

More »

GEN News Highlights

More »
May 30, 2007

Novacea and Schering-Plough Ink $440M Deal Related to Prostate Cancer Drug

  • Schering-Plough will aid Novacea in its development of Asentar, currently in a Phase III trial in patients with androgen-independent prostate cancer. The drug is a high-dose oral formulation of calcitriol, a potent hormone that exerts its effects through the vitamin D receptor.

    The exclusive, worldwide license agreement includes the development and commercialization of the Asentar. Novacea will receive an upfront payment of $60 million, including $35 million as reimbursement for past R&D expenses, a license fee of $25 million, and a commitment to purchase $12 million of Novacea common stock at a predetermined price within 10 days of the closing.

    Additionally, Novacea could earn precommercial milestone payments of up to $380 million and tiered royalties on worldwide sales.

    Schering-Plough will be responsible for all forward development costs in exploring indications for earlier stages of prostate cancer and will lead all global commercialization efforts for Asentar. Novacea will provide medical support to Schering-Plough's commercial operations for Asentar in the U.S., including deployment of their Medical Science Liaisons, which will be funded by Schering-Plough.

  • Finally! A cure for the Biotech News Blues.

  • Join 110,000 colleagues who rely on GEN Highlights for breaking news and exclusive articles shaping today’s life science tools and technologies.

  • Oops! Please type your email in the following format: yourname@example.com An error has occurred. Please contact Customer Service at contactGEN@genengnews.com
  • You’re all set! Thank you for subscribing to GEN Highlights.