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May 13, 2014

Infectious Disease Vaccines in the Omics Era

A shift from conventional vaccines to more rationally designed approaches is a hallmark of the new revolution.

Infectious Disease Vaccines in the Omics Era

Confocal microscopy image of trypomastigote forms of <i>T. cruzi</i> infecting a mammalian cell. Parasites (green) are labeled with anti-<i>T. cruzi</i> antibodies from chronic patients targeting sugar epitopes. [L.L. Nohara and I.C. Almeida]

Infectious diseases have shaped humanity more than any other single factor in history Despite the substantial morbidity and mortality associated with pathogens, eradicating infectious diseases has been challenging, both in terms of generating vaccines and in ensuring that immunization campaigns can be affordable, effective, and feasible on a global scale ...

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