Link Discovered between Blood Vessel Inflammation and Malfunctioning Mitochondria

Researchers at the Lewis Katz School of Medicine at Temple University have uncovered a novel mechanism by which abnormalities in mitochondrial fission in endothelial cells contribute to inflammation and oxidative stress in the cardiovascular system. They further show how the fission-fusion balance can be stabilized to lower inflammation using salicylate, the main active ingredient in everyday pain-relieving drugs like aspirin.