Researchers report that a pair of compounds originating from hops can help thwart a dangerous buildup of fat in the liver known as hepatic steatosis. The mouse-model study demonstrates that the compounds xanthohumol and tetrahydroxanthohumol, abbreviated to XN and TXN, can mitigate diet-induced accumulation of fat in the liver. The mechanism behind the compounds’ effectiveness involves PPARγ, a nuclear receptor protein, one that regulates gene expression.