New research in the journal Aging-US takes a closer look at the competitive endogenous RNA regulatory network to better understand complex gene interactions in hepatocellular carcinoma (HCC) and identify potential biomarkers to diagnose and treat HCC. Using RNA sequencing data available in public TCGA and GEO databases, they establish a seven-gene HCC signature and validate one hub gene in the prognostic signature, DTYMK, as a new potential biomarker.