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GEN videos are informative, entertaining, and encompass all aspects of biotechnology.

3D Microscopy of Immune Cell Migration in Zebrafish Ear

Nobel-prize-winning physicist Eric Betzig, Ph.D., recently lead a team to develop a revolutionary way of imaging live cells. As reported in Science, the Howard Hughes Medical Institute team used a combination of adaptive optics and lattice-sheet microscopy to create a 10-foot-long microscope for creating movies of living organisms. A tabletop version is currently in development.

  • 3D Microscopy of Immune Cell Migration in Zebrafish Ear

    Nobel-prize-winning physicist Eric Betzig, Ph.D., recently lead a team to develop a revolutionary way of imaging live cells. As reported in Science, the Howard Hughes Medical Institute team used a combination of adaptive optics and lattice-sheet microscopy to create a 10-foot-long microscope for creating movies of living organisms. A tabletop version is currently in development.

  • What Is Machine Learning?

    Many of the buzzwords thrown around in biotechnology these days come from computer science. One of these is “machine learning”. In this short video from the National Science Foundation, the CEO of Insightfinder explains the concept in simple terms.

  • Genotype-Tissue Expression Project

    GTEx is a large gene expression database with approximately 1,000 participants donating 50 tissue samples each. Researchers across the life sciences can use this as a baseline reference point for rare genetic diseases. The data easily accessible through the GTEx Portal website.

  • Mutating DNA Caught on Film

    Cellular mutations, it turns out are much more common than we thought. And fatal mutations, at least in bacteria, are far less common than we thought. This video from Science shows the tracking of spontaneous mutations of bacteria and their cell fate, using microfluidic chips.

  • GMO Yeast Makes Beer without Hops

    Hops. This single plant, originally an ale preservative, has been used to create the flowery flavor of beer that adults have enjoyed for millennia. Now, researchers at UCal Berkeley have used CRISPR/Cas9 technology to modify several strains of Saccharomyces Cerevisiae (Brewer’s Yeast) to produce a hoppy flavor without using the signature plant. In a blind taste test facilitated by the Lagunitas Brewing Company, testers detected notes of “fruit loops” and “orange blossom” in the GMO-made beer.

  • Tracking Live Cells Deep within Animals’ Bodies

    In this video by Science, scientists adapt firefly biology to create bioluminescent cells detectable from outside the body. In the future this technique could be used in medical imaging. It could help scientists know where stem cells end up, help in the success of gene editing, and track tumor growth.

  • Rapid Disease Detective

    In this video from The Broad Institute, two grad students from the lab of Feng Zhang, Ph.D., demonstrate rapid infectious disease testing using SHERLOCK (specific high-sensitivity enzymatic reporter unlocking) technology, a variant of CRISPR technology.

  • A Vaccine Against ... Cancer?

    “Cancer vaccine” is a major buzz-phase these days, and advancements have been featured on the pages of GEN many times. But what exactly is a cancer vaccine? This video from SciShow breaks down the science and some of the latest research into cancer-vaccine development into simple scientific terms.

  • Smart Contacts Can Monitor the Glucose in Tears

    Verily Life Sciences is exploring ways that biotech can improve treatments for all sorts of health conditions. In this video Bloomberg shows a smart contact lens that could provide diabetes patients with blood glucose data.

  • The Story of the Lab Rat

    The rat. Fellow mammal, plague bearer, beloved pet, and partner in science. In this video from The Good Stuff, learn about how the common brown rat (which terrorized Victorian London) became the lab rat we use today, and was even a pet of Queen Victoria.

  • Tumor-Related Immune Checkpoints And The Development Of Targeted Cancer Immunotherapies

    In this GEN video sponsored by OriGene, we'll learn how the emerging field of immuno-oncology is providing innovative new strategies to directly target and destroy cancer cells. These novel treatments are able to harness the power and specificity of the human immune system to detect and eliminate tumor cells. Immunotherapeutics can be combined with conventional chemotherapy to revolutionize the treatment of cancer…

  • Biomarker Based Companion Diagnostics Are Enabling Precision Oncology

    Cancer immunotherapy is a revolutionary treatment approach that mobilizes the patient's own immune system to destroy tumor cells. The human immune system is regulated in a highly orchestrated and balanced manner. This includes a negative feedback loop to regulate the activity of T cells. Tumor cells can take advantage of this to escape attack by the body's immune system…

    This GEN video is sponsored by OriGene

  • Robot Made of Algae Can Swim Through Your Body

    In this video by Science, scientists have manipulated spirulina, a microscopic plant and food supplement, to travel through people in response to magnetic signals. Thanks to magnets, this bio-hybrid bot could one day deliver drugs or do surgery.

  • Bacterial Snow Formation

    Oh! The weather outside is frightful! Thanks in part to bioprecipitation-forming bacteria. In this video from SciShow, learn about how microbes, including some plant pathogens, aid in the formation of ice crystals that cause snow.

  • Scientists Behaving Badly

    The history of science has had its fair share of mad experiments. Some experiments have been unethical, others have poor designs that throw findings into doubt, but some are literally self-inflicted. In this video from SciShow, we see six famous scientists who decided to take their work home with them in some truly cringe-worthy experiments.

  • Why Do Some People Hate Cilantro?

    Have you ever really hated a food that your friends said they absolutely loved? Well, in the case of cilantro (a small aromatic plant in the same family as carrots and celery), the answer might be in your genes. As shown in this video from the American Chemical Society, a percentage of humans have a gene which makes the herb taste like soap.

  • Gallo at 80: HIV Pioneer Still in the Lab

    Robert Gallo, M.D., is the co-discoverer of HIV. His research group demonstrated that HIV causes AIDS. He developed the HIV blood test. And he was the first to discover a human retrovirus (the human T cell leukemia virus). Today, at age 80, Dr. Gallo is the director of the University of Maryland Medical School’s Institute of Human Virology. He’s still in the lab—as shown in this video from the Institute—currently overseeing several studies, including an HIV vaccine.

  • The Problem with Lab Mice

    As the good book cautions us, “If you give a mouse a cookie, it’s going to want a glass of milk.” But what happens when the majority of pharmaceutical testing relies so heavily on the tiny shoulders of one animal model? This clip from “Adam Ruins Everything,” a fact-based comedy show from TruTV, illustrates some of the problems that come with outsourcing in vivo drug testing to a different species.

  • The Possibilities of CRISPR/Cas9

    CRISPR is everywhere recently, including the recent launch of The CRISPR Journal (published by Mary Ann Liebert, Inc.). But, clustered regularly interspaced short palindromic repeats is not the easiest thing to describe the layman, or even some people within the industry. This animated video from Nature beautifully illustrates how CRISPR/Cas9 can cut double-stranded DNA  for a variety of purposes.

  • Hacking Immune Cells

    In the 21st century, there must be a better way to treat cancer than chemotherapy, with all of its side effects. One method currently in development is T cell vector drug delivery. In this TEDtalk, UNC-Chapel Hill biochemist Elizabeth Wayne, Ph.D., describes using immune cells for cancer drug delivery through a combination of e-selectin and TRAIL (TNF-related apoptosis-inducing ligand).