Predicting TCR Specificity with Multiomic Single-Cell Sequencing

T cell receptors (TCRs) allow the adaptive immune system to recognize and respond to a vast array of threats, ranging from viruses to malignant cells. Single-cell sequencing has made it possible to explore an individual’s TCR repertoire and quantify changes due to an immune response. To fully unlock the great potential of these measurements we need to know which antigens each TCR binds.

In this GEN webinar, our distinguished presenter Dr. Peter Hawkins, will present a deep learning approach, that leverages highly multiplexed antigen binding experiments, to accurately predict the cognate antigens of TCRs and reveal distinct TCR binding motifs for individual antigens.

A live Q&A session will followed the presentation, offering a chance to pose questions to our expert panelist.