Originally Aired: March 14, 2023
Time: 8:00 am PT, 11:00 am ET, 17:00 CET

Phosphoproteomics is a cutting-edge research area that aims to understand the role of phosphorylation, a widespread modification of proteins, in regulating biological systems. Advances in mass spectrometry technology, sample preparation, and bioinformatics have led to the identification and quantification of more than 150,000 phosphorylation sites in the human proteome, providing a wealth of information about how proteins function in health and disease.

In this GEN webinar, our distinguished presenter, Dr. Florian Meier, will provide detailed insights into a new experimental approach that combines streamlined sample processing, dia-PASEF, and trapped ion mobility (TIMS) mass spectrometry to analyze the phosphoproteome of cancer cell lines. We will also learn about the key advantage of TIMS in reducing the number of co-isolated peptides by five-fold compared to traditional methods, resulting in a more efficient and effective analysis of the phosphoproteome. By the end of this webinar, we will have a deeper understanding of how dia-PASEF and TIMS mass spectrometry can contribute to the field of phosphoproteomics.

A live Q&A session followed the presentation, offering you a chance to pose questions to our expert panelist.

Bruker logo

Florian Meier
Florian Meier, PhD
Junior Professor
Jena University Hospital