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Exosomes from Heart Cells Can Be Therapeutic in Trauma Care

Capricor Therapeutics in collaboration with the U.S. Army Institute of Surgical Research report a preclinical study on a rat model of acute traumatic coagulopathy (ATC) where they have successfully administered cardiosphere-derived exosomes (CDC-EVs) to decrease post-trauma kidney damage, increase the growth of new blood vessels, reduce abnormally increased levels of lactate and creatinine, with no increase in clotting. The scientists believe CDC-EVs that do not require ultra-cold refrigeration could be the ideal product that can be delivered in the field to stabilize wounded warriors suffering from trauma.