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Acetylcholine Modulates Neural Activity to Parse Acoustic Signals

A new study reports modulation of neural activity by acetylcholine inputs helps parse tones from noise and may contribute to processing acoustic signals such as speech. The authors describe novel anatomical projections that provide cholinergic input to the brainstem auditory nucleus, MNTB. These cholinergic inputs enhance neural discrimination of critical tones such as speech from noise stimuli.

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