New research from the University of Tsukuba, Japan, shows that mice that have either low levels of a phosphatidylserine receptor called CD300a, or where CD300a is pharmacologically blocked, suffer limited neurological deficits after middle cerebral artery occlusion (MCAO)—a condition that recapitulates an ischemic stroke. These results open doors for potential new immunotherapies that can suppress stroke-related inflammation at its earliest stages, which often results in brain damage and permanent impairment.
Scientists in China have designed a new synthetic peptide that can protect neurons against the debilitating aftermath of both major types of strokes—ischemic and hemorrhagic—resulting in limited brain damage and neurological impairment. The current study demonstrates the efficacy and safety of the peptide in rhesus monkey and mouse models warranting human trials.
Making sure your plant-based diet consists of leafy greens and whole grains and not refined grains, potatoes and sugar, matters in estimating risk for stroke. A healthy plant-based diet is associated with a 10% reduction in risk for stroke, a new study reports.