A new neuroimaging study showed alterations of stress responses and self-regulatory inhibitory function associated with binge eating, but showed stress-induced failures of inhibitory control do not provide a comprehensive explanation for binge eating. Brain scans showed stress alters brain activity associated with inhibitory control in women with eating disorders but had no effect on their ability to stop their actions, suggesting more complex underlying causes for binge eating.
Exposure to inflammation promoting cytokines in the womb generated due to maternal stress during pregnancy differentially affects stress and immune regulatory brain circuitry in male and female offspring and retained into midlife. The study demonstrates a need for sex-dependent targets and therapeutics for early therapeutic intervention and prevention in neuropsychiatric disorders such as bipolar disorder, schizophrenia and major depression.
Researchers have released a large dataset on machine learning-based brain training called Decoded Neurofeedback (DecNef), a form of closed-loop fMRI neurofeedback combined with machine learning approaches that aims to alter brain dynamics and can benefit patients of PTSD, anxiety disorders, and other mental health conditions.