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Neuronal Code for How Humans Negotiate Their Environment Identified

Scientists at Columbia University and the University of California, Los Angeles are the first to demonstrate that phase precession, a time coding neuronal mechanism, plays a significant role in the human brain, and links not only sequential positions, as seen in earlier animal studies, but also abstract progression towards specific goals.

Study Identifies Vulnerable Neurons in Alzheimer’s Disease

Scientists characterize selectively vulnerable neuronal populations using single-nucleus RNA sequencing in postmortem brains spanning the progression of Alzheimer’s tau neurofibrillary pathology and identify RORB as a marker of selectively vulnerable excitatory neurons and decreased homeostatic gene expression in an astrocyte subpopulation.