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AI Finds Potential Drug Targets for Amyotrophic Lateral Sclerosis

A drug discovery initiative for amyotrophic lateral sclerosis (ALS) targets has used an AI-powered platform to identify 17 high-confidence and 11 new therapeutic targets for this devastating neurodegenerative disease that currently has no available treatment that reverses or stops its rapid progress. The study scans gene expression profiles in central nervous system samples from public datasets, and motor neurons derived directly from induced pluripotent stem cells.