Broadcast Date: December 8, 2021
Time: 8:00 am PT, 11:00 am ET, 1700 CET

The genetic medicine revolution is truly underway. The COVID-19 pandemic has allowed mRNA and DNA-based vaccines to show their true potential, but the industry has ongoing challenges to overcome. Almost all of today’s genetic medicines (mRNA, DNA vaccines, viral vectors) are dependent on plasmid DNA as either a critical starting material or API, which presents challenges in advanced therapy manufacturing. Although plasmid DNA has proven its worth, enabling the production and availability of vaccines, there is also a bottleneck in the industry with contract manufacturers who offer GMP quality plasmid DNA, resulting in a substantial supply restriction. The inability to provide quality DNA within tight timelines is a threat to the rapid progress of R&D pipelines. Moreover, antibiotic resistance genes in plasmid DNA are becoming a crucial global issue and a topic of increasing regulatory scrutiny.

In this GEN webinar, our distinguished presenters Dr. Tommy Duncan and Dr. Jill Makin, will address these industry challenges and discuss an alternative to plasmid DNA—a synthetic, antibiotic-free DNA vector called dbDNA™ (doggybone DNA). Additionally, we will learn how dbDNA can address the issues of traditional fermentation while achieving a significantly faster turnaround for GMP production and superior safety due to the elimination of bacterial sequences. With supportive case studies, this webinar will also explain how dbDNA is uniquely positioned to enable the rapid, global-scale DNA production that is so urgently required.

A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert panelists.

Tommy Duncan, PhD
Tommy Duncan, PhD
Chief Business Officer
Touchlight
Jill Makin, PhD
Jill Makin, PhD
Chief Development Officer
Touchlight

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