RNA Prestain Loading Dye

Staining for RNA is commonly done with EtBr on a denaturing gel after electrophoresis. However, denaturing gels can be complicated to prepare and involve handling hazardous reagents. RNA prestaining with EtBr can be performed with nondenaturing agarose gels but requires large amounts of the dye, and sensitivity is still limited. EMBER500™ was developed by Biotium scientists to offer brighter signals and higher sensitivity than EtBr for RNA gel staining. The prestain also includes formamide as well as electrophoresis tracking dyes, allowing sample denaturing, loading, tracking, and staining. The EMBER500™ also stains both RNA and DNA to allow the detection of contaminating genomic DNA in purified RNA samples.


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