The PurePep® Sonata® is a mid-pilot scale peptide synthesizer that has been designed to provide more reliable and robust workflows. PurePep Sonata introduces real-time flow technology to streamline and shorten fluid calibration workflows. The new system is an upgraded version of the previous SonataXT through the introduction of real-time flow technology. The synthesizer is built with seven solvent ports and twenty reagent ports to allow customization for any synthesis protocol. The company claims the icon-driven software simplifies the chemist’s workflow and accelerates the set-up of peptide synthesis methods. Pre-programmed methods may be used as is or as a template for customized methods, and sequences can be imported to avoid errors.