April 15, 2018 (Vol. 38, No. 8)
Three new recombinant Treponema pallidum antigens are now available for in vitro diagnostic (IVD) manufacturing and research applications. Treponema pallidum is a spirochete bacterium, with four known subspecies, responsible for treponemal diseases in humans, with syphilis being the most notable. The recombinant T. pallidum TpN-15, TpN-17, and TpN-47 antigens have all been expressly designed for use as an integral component within solid-phase enzyme immunoassay test procedures, especially ELISAs. The antigens are derived and sourced from Escherichia coli, via culture, which is then purified to a level of >95% and confirmed via SDS PAGE. These recombinant T. pallidum antigens are supplied preservative-free, demonstrate exceptional lot-to-lot consistencies, and feature an outstanding shelf life stability claim of four years from the date of manufacture. The antigens are available in a standard 0.2-mg fill-sized vial, with larger, bulk configurations also being available.