The NanoBrook Omni instrument offers a single powerful and accurate solution for particle sizing and zeta potential analysis. The instrument allows users to measure samples in nearly every possible suspension environment from high salts, such as PBS and sea water, to organic solvents and aqueous solutions. The instrument offers particle sizing, with high sensitivity, utilizing three light scattering measurement angles for truly unbiased measurement results. Applications that use iron oxide nanoparticles are vast and growing due to its stability, low toxicity, and magnetic properties. Given the great potential for applications using iron oxide, it is highly desirable to understand the effect of chemical changes to the surface of the nanoparticle. Aggregation of nanoparticles can occur due to changes in pH or temperature. Dynamic light Scattering offers a quick and easy way of determining the effective diameter of iron oxide nanoparticles and an autotitrator can help automate the process of detecting changes in particle size as a function of pH.