The high-capacity fixed-angle Rotor FA-6×250 for up to 6 x 250 mL bottles extends the application range of the large benchtop Centrifuges 5910 R and 5920 R, which encompasses harvesting of bacteria, algae, and yeast, as well as mammalian cells, in vessels up to 250 mL. An additional area of application now includes plasmid DNA extractions and lysate clearance following cell lysis. A broad selection of 12 different adapters minimizes the need for cumbersome rotor exchanges during the workflow; numerous vessel types of various volumes can now be accommodated by merely switching adapters. This simplifies handling and saves time. The 5910 R and 5920 R centrifuges also offer a large variety of rotors, thus serving countless applications in vessels ranging from 0.5 mL to 1.0 L in volume. In the past, the use of 250-mL flat-bottom bottles had been limited to swing-bucket rotors with a maximum speed just over 5,000 x g. The new fixed-angle rotor now delivers a speed of up to 15,054 x g, effectively extending the range of application of the large benchtop centrifuges.