New England Biolabs® announced the launch of the NEBNext Enzymatic 5hmC-seq Kit (E5hmC-seq™), a novel enzyme-based method for the specific detection of 5hmC sites. The company claims the enzyme-based approach enables high yields and high-quality data, with an input range of 100 pg to 200 ng. The kit includes the reagents required for E5hmC-seq conversion and library preparation compatible with Illumina sequencing; index primers for multiplexing are available separately. A conversion module is also available, for applications beyond library prep.