The NanoPhotometer® N120 is a new absorbance-based UV/VIS multi-channel spectrophotometer. The instrument’s compact and stand-alone design (20×20 cm) allows for rapid full scan analysis of up to 12 samples (2µl) at a time over a wide concentration range (2-8,000 ng/μL dsDNA). The N120 provides reliable data for the accurate determination of sample purity ratios, while reducing operational steps for the user by 33%. Powered by a 2.4 GHz Intel Celeron processor, the N120 significantly reduces measurement time, providing high-resolution full-scan data in as little as 1.7 seconds per sample. The NanoPhotometer can be easily incorporated into workflows by integration with any major LIMS provider for flexibility and added efficiency. Data export and device control can be executed directly through the LIMS interface on an external computer. Finally, the N120 can be combined with the new optional CFR21 software package, providing FDA 21 CFR Part 11 compliance for electronic records and electronic signatures.