September 1, 2014 (Vol. 34, No. 15)
Strong Points: Large collection of genes and drugs
Weak Points: No details provided for drug mechanisms
Vanderbilt University’s My Cancer Genome app provides a great deal of information related to the genetics of cancer and genetically informed cancer therapeutics. The app is divided into two sections. On the “variants” page users can browse (or search) diseases, genes, and gene variants. For example, selecting a specific disease displays a description of that type of cancer as well as a list of associated genes and variants. The other section of the app deals with drugs, allowing users to browse by drug name, drug class, or target. Unfortunately, selecting on a specific drug class (such as topoisomerase inhibitors) only directs users to a list of other drugs of that class, rather than providing additional details about the mechanism of action of that class of drug.