January 1, 2014 (Vol. 34, No. 1)
Strong Points: Clean design, citations given
Weak Points: No easy visualization of molecule specificity
Kinases play an important role in cell signaling, metabolism, and…well…basically everything. Whether for the purpose of manipulating kinase activity in the lab or for therapeutic purposes, it is useful to identify molecules that can bind to, and modulate the activity of, specific kinases. The iKinase Universal app gives users access to the Eidogen-Sertanty Kinase Knowledgebase, a database of small molecules that target kinases. The information in the app is organized alphabetically by the name of the kinase target. Upon selection of a kinase, users can browse the various molecules that target that specific enzyme. Brief information is given about the experiment in which that molecule was tested, and the title and complete reference to any corresponding publication is given. Clicking on the reference takes users directly to PubMed.