May 15, 2018 (Vol. 38, No. 10)
Strong Points: Nicely organized, incredibly large database
Weak Points: None
Funded by the National Institute of Allergy and Infectious Diseases, the Immune Epitope Database and Analysis Resource (IEDB) provides the immunology community a rich collection of experimental data (we’re talking hundreds of thousands of assays) reflecting the study of T-cell epitopes and antibodies. To start, users can search the database by epitope, assay type, antigen, MHC classification, host, or disease. These search parameters can also be used in conjunction to filter search results as desired. Results are presented in different tabs corresponding to epitopes, antigens, assays, receptors, and references, and within each tab, the user can further sort the results. Beyond the database itself, the website includes analysis tools like T-cell and B-cell epitope predictors, as well as additional epitope analysis tools to calculate, for example, the proportion of individuals within a population predicted to respond to a particular epitope.